Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum.

نویسندگان

  • Daniel D Mosel
  • Raluca Dumitru
  • Jacob M Hornby
  • Audrey L Atkin
  • Kenneth W Nickerson
چکیده

Concentrations of (E,E)-farnesol needed to inhibit germ tube formation were determined for Candida albicans strains A72 and SC5314 by using six different conditions known to trigger germination. For defined media, 1 to 2 microM farnesol was sufficient. However, with serum at 2 to 20%, up to 250 microM farnesol was required. Farnesol blocked germ tube formation but did not block elongation of existing germ tubes.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 71 8  شماره 

صفحات  -

تاریخ انتشار 2005